Lack of in vitro antimicrosporidian activity of thalidomide.
نویسندگان
چکیده
Thalidomide was evaluated for its in vitro activity against Encephalitozoon species by using the MRC-5 cell system. A cytotoxic effect was observed for concentrations of 10(1) microg/ml (P < 10(5)) and 5 microg/ml (P < 10(5)). Thalidomide did not significantly inhibit the growth of any of the microsporidia under study. These data suggest that thalidomide is not an etiologic treatment in microsporidial enteritis.
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 43 9 شماره
صفحات -
تاریخ انتشار 1999